11/1/2015
Complications of TVT and TOT
Registered users can also download a PDF or listen to a podcast of this Pearl.
Log in now, or create a free account to access bonus Pearls features.
Tension-free transvaginal tape (TVT) and transobturator tape (TOT) are polypropylene mesh “slings” placed in a midurethral position to treat stress incontinence. TVT incorporates a retropubic approach with the tape exiting the anterior abdominal wall along the superior border of the pubic symphysis. TOT is placed via the obturator foramina, exiting in the groin. Both are generally safe with success rates approaching 80% for either technique. There are several complications:
- Bladder perforation is more common with TVT due to passage of needles through the retropubic space. Intra-operative cystoscopy is required for timely diagnosis. If perforation is identified, the needle should be removed and careful re-insertion may be attempted. Foley catheter drainage is often recommended for at least 24 hours and antibiotics may be indicated.
- Transient urinary retention/incomplete emptying is common, typically caused by urethral obstruction from the mesh. An intra-operative stress test may help reduce this problem in awake patients, allowing loosening of the mesh as needed. Management with post-operative catheter drainage with voiding trials every 2-3 days is recommended. Most cases resolve within 10-14 days. Persistent urinary problems occur in 1-2% of patients, often requiring surgical release of the mesh. Most of these patients have preservation of continence.
- Urge Incontinence/urgency occurs in approximately 25% of patients with TVT, but is less common with the TOT. Initially, patients can be managed expectantly or with behavioral or pharmacologic therapy. Most patients will have partial or complete resolution within 4-6 weeks.
- Post-operative infection may occur as either a urinary tract infection or wound infection. Patients with pain, erythema, fever, or other evidence of infection must be carefully evaluated for either wound infection or urinary tract infection. Antibiotics are typically effective, but removal of the mesh may be necessary for refractory cases.
- Hemorrhage due to venous or arterial injury during needle passage may result in post-operative hematomas that can usually be managed conservatively. Rapid intra- or post-operative hemodynamic instability may be evidence of major vascular injury and rapid intervention is mandatory.
- Mesh erosion may occur despite appropriate mesh placement. Evidence of bladder or urethral erosion includes hematuria, recurrent urinary tract infections, and pain. Vaginal erosion symptoms include pelvic pain, discharge, and dyspareunia. Mesh excision is often required, although conservative approaches may be appropriate.
- Vaginal injury is more common with TOT due to the course of the needle near the vaginal fornices. Primary repair intra-operatively resolves most problems.
- Pain/nerve injury is more common with TOT due to puncture of the muscular pelvic sidewall. Initial management is conservative. Mesh excision may be required for refractory cases.
- Bowel injury is a rare but potentially catastrophic complication that remains hard to recognize intra-operatively.
TVT and TOT are generally safe and effective minimally invasive interventions for stress incontinence. Long term, 4-8% of patients may experience reoperation for stress incontinence, tape erosion or extrusion, or groin pain. Careful adherence to correct surgical technique and respect for pelvic anatomy will help prevent most complications. Appropriate and timely intervention will minimize the long-term sequelae when complications do occur.
Further reading:
Committee on Practice Bulletins—Gynecology and the American Urogynecologic Society. ACOG Practice Bulletin No. 155: Urinary Incontinence in Women. Obstet Gynecol. 2015 Nov;126(5):e66-81. doi: 10.1097/AOG.0000000000001148.
Ford AA, Rogerson L, Cody JD, et al, Mid-urethral sling operations for stress urinary incontinence in women. Cochrane Database Syst Rev. 2017 Jul 31;7:CD006375. doi: 10.1002/14651858.CD006375.pub4.
Salo, H., Sova, H., Laru, J. et al. Long-term results of a prospective randomized trial comparing tension-free vaginal tape versus transobturator tape in stress urinary incontinence. Int Urogynecol J (2023). https://doi.org/10.1007/s00192-023-05527-z
Initial Approval: April 2011; Revised September 2018; Reaffirmed March 2020; Reaffirmed November 2021; Minor edits September 2023
********** Notice Regarding Use ************
The Society for Academic Specialists in General Obstetrics and Gynecology, Inc. (“SASGOG”) is committed to accuracy and will review and validate all Pearls on an ongoing basis to reflect current practice.
This document is designed to aid practitioners in providing appropriate obstetric and gynecologic care. Recommendations are derived from major society guidelines and high-quality evidence when available, supplemented by the opinion of the author and editorial board when necessary. It should not be construed as dictating an exclusive course of treatment or procedure to be followed.
Variations in practice may be warranted when, in the reasonable judgment of the treating clinician, such course of action is indicated by the condition of the patient, limitations of available resources, or advances in knowledge or technology. SASGOG reviews the articles regularly; however, its publications may not reflect the most recent evidence. While we make every effort to present accurate and reliable information, this publication is provided “as is” without any warranty of accuracy, reliability, or otherwise, either express or implied. SASGOG does not guarantee, warrant, or endorse the products or services of any firm, organization, or person. Neither SASGOG nor its respective officers, directors, members, employees, or agents will be liable for any loss, damage, or claim with respect to any liabilities, including direct, special, indirect, or consequential damages, incurred in connection with this publication or reliance on the information presented.
Copyright 2023 The Society for Academic Specialists in General Obstetrics and Gynecology, Inc. All rights reserved. No re-print, duplication or posting allowed without prior written consent.
Back to Search Results